UC researchers to study presence of MRSA in air in hospital settings
College of Medicine, Nursing researchers receive grant to conduct environmental surveillance
Even in a post-pandemic world, frontline health care workers face many occupational challenges, and exposure to infection is among them.
Now, University of Cincinnati scientists are working to minimize health care workers’ exposure to MRSA, or methicillin-resistant Staphylococcus aureus, a type of staph bacteria that's become resistant to many of the antibiotics used to treat ordinary staph infections.
Most MRSA infections occur in people who've been in hospitals or other health care settings, making it a particular risk to those who work in such facilities, and a team of UC researchers has been awarded a $300,000 grant from the Ohio Bureau of Workers’ Compensation to conduct environmental surveillance at University of Cincinnati Medical Center.
MRSA is primarily transmitted through person-to-person contact and contact with contaminated surfaces, but experts have emerging evidence of the presence of MRSA in the air in hospital settings. As of 2021, Ohio had an incidence of MRSA that's greater than the national incidence, according to the state department of health.
Sripriya Nannu Shankar, PhD/Photo/provided
The study’s lead author is Sripriya Nannu Shankar, PhD, assistant professor in the Division of Environmental and Industrial Hygiene in the Department of Environmental and Public Health Sciences at the College of Medicine. Shankar and colleagues will try to get a better grasp on the presence of MRSA in the air and the significance of airborne transmission of MRSA.
Researchers will conduct laboratory and field work at UC Medical Center, where an air sampler in three of the units will collect particles laden with microbes.
Even if MRSA is detected, Shankar said UC Medical Center employees can be assured that their risk is low with current control measures.
“As we know from COVID-19 research, mere detection of a pathogen doesn't mean it can cause infection,” she said. “The microbe should be live or viable to cause an infection.”
Researchers will also study the effectiveness of the current control measures, which include regular testing of admitted patients, periodic disinfection and high air exchange rates within the hospital. They will also study the effectiveness of alternate methods of inactivating MRSA, such as UVC light sterilizers, disinfectant sprays and air purifiers.
Shankar explained that if researchers discover that MRSA is live, they will follow protocols to disinfect the air and make recommendations to further enhance workplace safety.
“Our team will also seek input from hospital workers about current protocols and potential changes in the future,” she said. “We expect existing policies to minimize the risk of MRSA exposure to workers and patients. Our study gives an added layer of confidence that the risk of exposure to MRSA is minimal to none in their units.”
One of Shankar’s collaborators explained the significance of how they are conducting their work.
“Understanding this unique environment is key to being able to collect samples and interact with hospital staff,” said Elizabeth Bien, PhD, assistant professor in the College of Nursing. “As a previous infection preventionist and an occupational health nurse who was trained to focus on the worker as a patient, I am excited to partner on this work.”
The study team also includes Jagjit Yadav, PhD, from the Department of Environmental and Public Health Sciences; Vivek Narendran, MD, in the Division of Neonatology in the Department of Pediatrics and a Cincinnati Children’s Hospital physician; and industry collaborator Arantzazu Eiguren-Fernandez, senior research chemist at Aerosol Dynamics Inc.
Featured image at top: A Petri dish with bacteria growing inside. Photo/Provided
Impact Lives Here
The University of Cincinnati is leading public urban universities into a new era of innovation and impact. Our faculty, staff and students are saving lives, changing outcomes and bending the future in our city's direction. Next Lives Here.
Related Stories
Sugar overload killing hearts
November 10, 2025
Two in five people will be told they have diabetes during their lifetime. And people who have diabetes are twice as likely to develop heart disease. One of the deadliest dangers? Diabetic cardiomyopathy. But groundbreaking University of Cincinnati research hopes to stop and even reverse the damage before it’s too late.
Is going nuclear the solution to Ohio’s energy costs?
November 10, 2025
The Ohio Capital Journal recently reported that as energy prices continue to climb, economists are weighing the benefits of going nuclear to curb costs. The publication dove into a Scioto Analysis survey of 18 economists to weigh the pros and cons of nuclear energy. One economist featured was Iryna Topolyan, PhD, professor of economics at the Carl H. Lindner College of Business.
App turns smartwatch into detector of structural heart disease
November 10, 2025
An app that uses an AI model to read a single-lead ECG from a smartwatch can detect structural heart disease, researchers reported at the 2025 Scientific Sessions of the American Heart Association. Although the technology requires further validation, researchers said it could help improve the identification of patients with heart failure, valvular conditions and left ventricular hypertrophy before they become symptomatic, which could improve the prognosis for people with these conditions.