Bioengineer.org: University of Cincinnati researcher says proteins in patients biomarkers of heart disease

Blood test could someday identify plasma protein in diabetic patients at risk of heart disease

Bioengineer.org highlighted research findings from a University of Cincinnati cardiologist who found that plasma proteins discovered in the blood samples of diabetic patients who went on to develop obstructive coronary disease (OCAD) serve as biomarkers of future heart disease.

Lynch, an assistant professor in the UC College of Medicine looked at blood samples from 75 diabetic patients: two groups of 35 with one group eventually developing obstructive coronary disease while the other group did not. A total of 248 plasma proteins were identified; 15 were present only in patients with obstructive coronary disease while three were present in patients without OCAD.

“We took samples of plasma and used mass spectrometry to see if we could find biomarkers that were predictive of patients developing obstructive coronary disease,” says Lynch.  “The significance of this is I see patients who have diabetes and unfortunately develop blockages but no symptoms.”

Read the full story in Bioengineer.org

Learn more about research from Donald Lynch, MD.

Featured image of blood in test tubes is courtesy of Unsplash.

Related Stories

1

Sugar overload killing hearts

November 10, 2025

Two in five people will be told they have diabetes during their lifetime. And people who have diabetes are twice as likely to develop heart disease. One of the deadliest dangers? Diabetic cardiomyopathy. But groundbreaking University of Cincinnati research hopes to stop and even reverse the damage before it’s too late.

2

Is going nuclear the solution to Ohio’s energy costs?

November 10, 2025

The Ohio Capital Journal recently reported that as energy prices continue to climb, economists are weighing the benefits of going nuclear to curb costs. The publication dove into a Scioto Analysis survey of 18 economists to weigh the pros and cons of nuclear energy. One economist featured was Iryna Topolyan, PhD, professor of economics at the Carl H. Lindner College of Business.

3

App turns smartwatch into detector of structural heart disease

November 10, 2025

An app that uses an AI model to read a single-lead ECG from a smartwatch can detect structural heart disease, researchers reported at the 2025 Scientific Sessions of the American Heart Association. Although the technology requires further validation, researchers said it could help improve the identification of patients with heart failure, valvular conditions and left ventricular hypertrophy before they become symptomatic, which could improve the prognosis for people with these conditions.